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One or more keywords matched the following properties of Lilly, Michael
PropertyValue
keywords Drug Studies
keywords Men-s Health
keywords Healthy Volunteer Studies
One or more keywords matched the following items that are connected to Lilly, Michael
Item TypeName
Academic Article Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
Academic Article Concept formation and problem-solving following closed head injury in children.
Academic Article Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Academic Article Cytoplasmic domains of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor beta chain (hbetac) responsible for human GM-CSF-induced myeloid cell differentiation.
Academic Article Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation.
Academic Article The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
Academic Article The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
Academic Article Bryostatin 1: a potential anti-leukemic agent for chronic myelomonocytic leukemia.
Academic Article Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
Academic Article Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway.
Academic Article The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.
Academic Article PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.
Academic Article Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
Academic Article PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications.
Academic Article Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia.
Academic Article Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer.
Academic Article Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
Academic Article Production of granulocyte colony-stimulating factor by a human melanoma cell line.
Academic Article Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2.
Academic Article Effect of granulocyte-macrophage colony-stimulating factor and interleukin-3 on interleukin-8 production by human neutrophils and monocytes.
Academic Article Mapping the intracytoplasmic regions of the alpha granulocyte-macrophage colony-stimulating factor receptor necessary for cell growth regulation.
Academic Article Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.
Academic Article Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival.
Academic Article Pim family kinases enhance tumor growth of prostate cancer cells.
Academic Article Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase.
Academic Article Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
Academic Article Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.
Academic Article Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
Academic Article Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75.
Academic Article Differentiation and growth modulation of chronic myelogenous leukemia cells by bryostatin.
Academic Article Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Academic Article Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study.
Academic Article p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
Academic Article Regulation of Skp2 levels by the Pim-1 protein kinase.
Academic Article Differential expression of peroxiredoxins in prostate cancer: consistent upregulation of PRDX3 and PRDX4.
Academic Article Combination therapy of recurrent prostate cancer with the proteasome inhibitor bortezomib plus hormone blockade.
Academic Article Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins.
Academic Article Moving on up: Second-Line Agents as Initial Treatment for Newly-Diagnosed Patients with Chronic Phase CML.
Academic Article Kava components down-regulate expression of AR and AR splice variants and reduce growth in patient-derived prostate cancer xenografts in mice.
Academic Article A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy.
Academic Article Leukemia-differentiating activity expressed by the human melanoma cell line LD-1.
Academic Article Sustained expression of the pim-1 kinase is specifically induced in myeloid cells by cytokines whose receptors are structurally related.
Academic Article The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation.
Concept Tandem Mass Spectrometry
Concept Problem Solving
Concept Drug Administration Schedule
Concept Protein Subunits
Concept Granulocyte Colony-Stimulating Factor
Concept RNA, Small Interfering
Concept Health Services Accessibility
Concept Neoplastic Stem Cells
Concept Tumor Suppressor Protein p53
Concept Stereoisomerism
Concept Sphingolipids
Concept Oncogenes
Concept S-Phase Kinase-Associated Proteins
Concept Mutagenesis, Site-Directed
Concept Health Services Research
Concept Quantitative Structure-Activity Relationship
Concept Sensitivity and Specificity
Concept Cell Survival
Concept Receptors, Cell Surface
Concept Proto-Oncogenes
Concept Genes, Dominant
Concept Glasgow Coma Scale
Concept Ribosomal Protein S6 Kinases
Concept Sirolimus
Concept Computer Simulation
Concept STAT5 Transcription Factor
Concept Amino Acid Sequence
Concept Disease-Free Survival
Concept Health Status
Concept Drug Delivery Systems
Concept Cohort Studies
Concept src-Family Kinases
Concept United States Department of Veterans Affairs
Concept STAT3 Transcription Factor
Concept Tumor Stem Cell Assay
Concept Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
Concept Prostate-Specific Antigen
Concept Shc Signaling Adaptor Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept Spectrometry, Mass, Electrospray Ionization
Concept Protein Synthesis Inhibitors
Concept Emergency Service, Hospital
Concept Static Electricity
Concept Molecular Structure
Concept Intercellular Signaling Peptides and Proteins
Concept Growth Substances
Concept Retrospective Studies
Concept Repetitive Sequences, Nucleic Acid
Concept Sequence Deletion
Concept Health Expenditures
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Genes, p53
Concept Drug Synergism
Concept Signal Transduction
Concept Protein Structure, Secondary
Concept Sarcoma
Concept Transgenes
Concept Hematopoietic Stem Cells
Concept Protein Structure, Tertiary
Concept Adaptor Proteins, Signal Transducing
Concept Longitudinal Studies
Concept Health Care Costs
Concept Life Style
Concept Survival Analysis
Concept Cellular Senescence
Concept Paraneoplastic Syndromes
Concept Binding Sites
Concept Salvage Therapy
Concept Mice, SCID
Concept Case-Control Studies
Concept Mice, Inbred Strains
Concept Genes, abl
Concept Neoplasm Staging
Concept Macromolecular Substances
Concept Cross-Sectional Studies
Concept Simian virus 40
Concept Stromal Cells
Concept Substrate Specificity
Concept Oligonucleotide Array Sequence Analysis
Concept United States
Concept Serine
Concept Colony-Stimulating Factors
Concept Skin Neoplasms
Concept Structure-Activity Relationship
Concept Base Sequence
Concept Follow-Up Studies
Concept Molecular Sequence Data
Academic Article Recovery of renal function among ESRD patients in the US medicare program.
Academic Article Generation of "virtual" control groups for single arm prostate cancer adjuvant trials.
Academic Article Antibody-mediated p53 protein therapy prevents liver metastasis in vivo.
Academic Article Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis.
Academic Article The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.
Academic Article Sodium vanadate, a tyrosine phosphatase inhibitor, affects expression of hematopoietic growth factors and extracellular matrix RNAs in SV40-transformed human marrow stromal cells.
Academic Article Stakeholder perspectives on transitions of nursing home residents to hospital emergency departments and back in two Canadian provinces.
Academic Article SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.
Academic Article Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model.
Academic Article Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphoma.
Academic Article Discordance in perceived risk and epidemiological outcomes of prostate cancer among African American men.
Academic Article Development of cell-penetrating bispecific antibodies targeting the N-terminal domain of androgen receptor for prostate cancer therapy.
Academic Article Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue.
Academic Article Advanced glycation end products are elevated in estrogen receptor-positive breast cancer patients, alter response to therapy, and can be targeted by lifestyle intervention.
Academic Article Identification of Incidental Germline Mutations in Patients With Advanced Solid Tumors Who Underwent Cell-Free Circulating Tumor DNA Sequencing.
Academic Article Circulating tumor DNA alterations in patients with metastatic castration-resistant prostate cancer.
Academic Article Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-?.
Academic Article Routine Plasma-Based Genotyping to Comprehensively Detect Germline, Somatic, and Reversion BRCA Mutations among Patients with Advanced Solid Tumors.
Academic Article Circulating-tumor DNA as predictor of enzalutamide response post-abiraterone treatment in metastatic castration-resistant prostate cancer.
Academic Article Financial toxicity and strain among men receiving prostate cancer care in an equal access healthcare system.
Academic Article Co-morbidities in a Retrospective Cohort of Prostate Cancer Patients.
Academic Article Social and clinical determinants of physical activity in prostate cancer survivors.
Academic Article Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer.
Concept High-Throughput Nucleotide Sequencing
Concept TOR Serine-Threonine Kinases
Concept Molecular Docking Simulation
Concept Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome
Concept Social Determinants of Health
Concept Cancer Survivors
Concept Src Homology 2 Domain-Containing, Transforming Protein 1
Academic Article The Pathologic Role of Toll-Like Receptor 4 in Prostate Cancer.
Academic Article Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies.
Academic Article A phase II study of docetaxel plus lycopene in metastatic castrate resistant prostate cancer.
Academic Article RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans.
Academic Article Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration-resistant prostate cancer.
Academic Article Differential Circulating Fungal Microbiome in Prostate Cancer Patients Compared to Healthy Control Individuals.
Academic Article Comprehensive Genomic Profiling of Cell-Free DNA in Men With Advanced Prostate Cancer: Differences in Genomic Landscape Based on Race.
Academic Article Racial Distribution of Neighborhood-Level Social Deprivation in a Retrospective Cohort of Prostate Cancer Survivors.
Academic Article Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis.
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