Item Type | Name |
Academic Article
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Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
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Academic Article
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Concept formation and problem-solving following closed head injury in children.
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Academic Article
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Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
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Academic Article
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Cytoplasmic domains of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor beta chain (hbetac) responsible for human GM-CSF-induced myeloid cell differentiation.
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Academic Article
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Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation.
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Academic Article
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The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
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Academic Article
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The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
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Academic Article
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Bryostatin 1: a potential anti-leukemic agent for chronic myelomonocytic leukemia.
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Academic Article
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Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
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Academic Article
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Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway.
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Academic Article
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The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.
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Academic Article
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PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.
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Academic Article
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Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
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Academic Article
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PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications.
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Academic Article
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Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia.
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Academic Article
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Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer.
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Academic Article
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Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
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Academic Article
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Production of granulocyte colony-stimulating factor by a human melanoma cell line.
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Academic Article
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Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2.
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Academic Article
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Effect of granulocyte-macrophage colony-stimulating factor and interleukin-3 on interleukin-8 production by human neutrophils and monocytes.
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Academic Article
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Mapping the intracytoplasmic regions of the alpha granulocyte-macrophage colony-stimulating factor receptor necessary for cell growth regulation.
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Academic Article
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Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.
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Academic Article
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Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival.
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Academic Article
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Pim family kinases enhance tumor growth of prostate cancer cells.
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Academic Article
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Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase.
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Academic Article
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Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
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Academic Article
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Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.
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Academic Article
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Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
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Academic Article
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Docetaxel-induced prostate cancer cell death involves concomitant activation of caspase and lysosomal pathways and is attenuated by LEDGF/p75.
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Academic Article
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Differentiation and growth modulation of chronic myelogenous leukemia cells by bryostatin.
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Academic Article
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Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
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Academic Article
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Dasatinib 140 mg once daily versus 70 mg twice daily in patients with Ph-positive acute lymphoblastic leukemia who failed imatinib: Results from a phase 3 study.
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Academic Article
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p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
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Academic Article
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Regulation of Skp2 levels by the Pim-1 protein kinase.
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Academic Article
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Differential expression of peroxiredoxins in prostate cancer: consistent upregulation of PRDX3 and PRDX4.
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Academic Article
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Combination therapy of recurrent prostate cancer with the proteasome inhibitor bortezomib plus hormone blockade.
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Academic Article
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Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins.
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Academic Article
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Moving on up: Second-Line Agents as Initial Treatment for Newly-Diagnosed Patients with Chronic Phase CML.
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Academic Article
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Kava components down-regulate expression of AR and AR splice variants and reduce growth in patient-derived prostate cancer xenografts in mice.
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Academic Article
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A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy.
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Academic Article
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Leukemia-differentiating activity expressed by the human melanoma cell line LD-1.
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Academic Article
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Sustained expression of the pim-1 kinase is specifically induced in myeloid cells by cytokines whose receptors are structurally related.
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Academic Article
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The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation.
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Concept
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Tandem Mass Spectrometry
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Concept
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Problem Solving
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Concept
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Drug Administration Schedule
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Concept
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Protein Subunits
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Concept
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Granulocyte Colony-Stimulating Factor
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Concept
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RNA, Small Interfering
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Concept
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Health Services Accessibility
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Concept
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Neoplastic Stem Cells
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Concept
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Tumor Suppressor Protein p53
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Concept
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Stereoisomerism
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Concept
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Sphingolipids
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Concept
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Oncogenes
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Concept
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S-Phase Kinase-Associated Proteins
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Concept
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Mutagenesis, Site-Directed
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Concept
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Health Services Research
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Concept
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Quantitative Structure-Activity Relationship
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Concept
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Sensitivity and Specificity
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Concept
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Cell Survival
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Concept
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Receptors, Cell Surface
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Concept
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Proto-Oncogenes
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Concept
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Genes, Dominant
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Concept
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Glasgow Coma Scale
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Concept
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Ribosomal Protein S6 Kinases
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Concept
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Sirolimus
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Concept
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Computer Simulation
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Concept
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STAT5 Transcription Factor
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Concept
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Amino Acid Sequence
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Concept
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Disease-Free Survival
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Concept
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Health Status
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Concept
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Drug Delivery Systems
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Concept
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Cohort Studies
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Concept
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src-Family Kinases
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Concept
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United States Department of Veterans Affairs
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Concept
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STAT3 Transcription Factor
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Concept
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Tumor Stem Cell Assay
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Concept
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Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
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Concept
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Prostate-Specific Antigen
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Concept
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Shc Signaling Adaptor Proteins
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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Spectrometry, Mass, Electrospray Ionization
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Concept
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Protein Synthesis Inhibitors
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Concept
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Emergency Service, Hospital
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Concept
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Static Electricity
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Concept
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Molecular Structure
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Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Growth Substances
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Concept
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Retrospective Studies
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Concept
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Repetitive Sequences, Nucleic Acid
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Concept
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Sequence Deletion
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Concept
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Health Expenditures
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Concept
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Granulocyte-Macrophage Colony-Stimulating Factor
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Concept
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Genes, p53
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Concept
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Drug Synergism
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Concept
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Signal Transduction
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Concept
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Protein Structure, Secondary
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Concept
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Sarcoma
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Concept
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Transgenes
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Concept
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Hematopoietic Stem Cells
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Concept
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Protein Structure, Tertiary
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Concept
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Adaptor Proteins, Signal Transducing
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Concept
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Longitudinal Studies
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Concept
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Health Care Costs
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Concept
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Life Style
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Concept
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Survival Analysis
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Concept
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Cellular Senescence
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Concept
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Paraneoplastic Syndromes
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Concept
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Binding Sites
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Concept
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Salvage Therapy
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Concept
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Mice, SCID
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Concept
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Case-Control Studies
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Concept
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Mice, Inbred Strains
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Concept
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Genes, abl
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Concept
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Neoplasm Staging
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Concept
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Macromolecular Substances
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Concept
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Cross-Sectional Studies
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Concept
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Simian virus 40
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Concept
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Stromal Cells
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Concept
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Substrate Specificity
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Concept
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Oligonucleotide Array Sequence Analysis
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Concept
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United States
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Concept
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Serine
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Concept
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Colony-Stimulating Factors
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Concept
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Skin Neoplasms
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Concept
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Structure-Activity Relationship
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Concept
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Base Sequence
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Concept
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Follow-Up Studies
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Concept
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Molecular Sequence Data
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Academic Article
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Recovery of renal function among ESRD patients in the US medicare program.
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Academic Article
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Generation of "virtual" control groups for single arm prostate cancer adjuvant trials.
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Academic Article
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Antibody-mediated p53 protein therapy prevents liver metastasis in vivo.
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Academic Article
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Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis.
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Academic Article
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The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.
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Academic Article
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Sodium vanadate, a tyrosine phosphatase inhibitor, affects expression of hematopoietic growth factors and extracellular matrix RNAs in SV40-transformed human marrow stromal cells.
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Academic Article
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Stakeholder perspectives on transitions of nursing home residents to hospital emergency departments and back in two Canadian provinces.
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Academic Article
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SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.
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Academic Article
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Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model.
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Academic Article
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Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphoma.
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Academic Article
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Discordance in perceived risk and epidemiological outcomes of prostate cancer among African American men.
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Academic Article
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Development of cell-penetrating bispecific antibodies targeting the N-terminal domain of androgen receptor for prostate cancer therapy.
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Academic Article
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Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue.
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Academic Article
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Advanced glycation end products are elevated in estrogen receptor-positive breast cancer patients, alter response to therapy, and can be targeted by lifestyle intervention.
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Academic Article
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Identification of Incidental Germline Mutations in Patients With Advanced Solid Tumors Who Underwent Cell-Free Circulating Tumor DNA Sequencing.
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Academic Article
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Circulating tumor DNA alterations in patients with metastatic castration-resistant prostate cancer.
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Academic Article
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Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-?.
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Academic Article
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Routine Plasma-Based Genotyping to Comprehensively Detect Germline, Somatic, and Reversion BRCA Mutations among Patients with Advanced Solid Tumors.
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Academic Article
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Circulating-tumor DNA as predictor of enzalutamide response post-abiraterone treatment in metastatic castration-resistant prostate cancer.
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Academic Article
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Financial toxicity and strain among men receiving prostate cancer care in an equal access healthcare system.
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Academic Article
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Co-morbidities in a Retrospective Cohort of Prostate Cancer Patients.
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Academic Article
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Social and clinical determinants of physical activity in prostate cancer survivors.
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Academic Article
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Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer.
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Concept
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High-Throughput Nucleotide Sequencing
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Concept
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TOR Serine-Threonine Kinases
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Concept
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Molecular Docking Simulation
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Concept
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Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome
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Concept
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Social Determinants of Health
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Concept
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Cancer Survivors
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Concept
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Src Homology 2 Domain-Containing, Transforming Protein 1
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Academic Article
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The Pathologic Role of Toll-Like Receptor 4 in Prostate Cancer.
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Academic Article
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Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies.
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Academic Article
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A phase II study of docetaxel plus lycopene in metastatic castrate resistant prostate cancer.
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Academic Article
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RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans.
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Academic Article
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Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration-resistant prostate cancer.
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Academic Article
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Differential Circulating Fungal Microbiome in Prostate Cancer Patients Compared to Healthy Control Individuals.
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Academic Article
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Comprehensive Genomic Profiling of Cell-Free DNA in Men With Advanced Prostate Cancer: Differences in Genomic Landscape Based on Race.
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Academic Article
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Racial Distribution of Neighborhood-Level Social Deprivation in a Retrospective Cohort of Prostate Cancer Survivors.
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Academic Article
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Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis.
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